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Hyperphosphorylated tau detaches from microtubules, aggregates, and forms paired helical filaments, leading to the collapse of the neuronal transport system and subsequent neurodegeneration (Han et al
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Gong S., Cai X., Wang Y., et al., “Botch Improves Cognitive Impairment After Cerebral Ischemia Associated With Microglia‐Induced A1‐Type Astrocyte Activation,” Neurobiology of Disease 201 (2024): 106684